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All Truth passes through Three Stages: First,
it is Ridiculed. Second, it is Violently Opposed... Third, it is Accepted as being Self-Evident.
- Arthur Schopenhauer (1778-1860) By Charly Groenendijk           Back to Side-Effects
The Netherlands
2000 - 2009

 
  Lexapro or Cipralex (Escitalopram) Side-Effects  
 

"Who does Not Know the Truth, is simply a Fool...
Yet who Knows the Truth and Calls it a Lie, is a Criminal."
- In "Galileo Galilei" by Berthold Brecht (1898-1956)

Doctors & Health Insurers fall for the old "optical isomer trick." Lexapro/Cipralex (escitalopram) is merely the active "Optical Isomer" of Celexa/Cipramil (citalopram). Other terms for "Optical Isomer" are "Stereoisomer" and "Enantiomer". The two optical isomers of citalopram are just mirror images of one another. The fault is not really the physicians': Forest Laboratories has generally skipped the simple explanation that for all intents and purposes Lexapro/Cipralex is identical to Celexa/Cipramil, except that you only need to give half as much. Rather, news releases have implied that escitalopram is a completely novel compound. Introducing the active stereoisomer around the time that the racemic mixture goes off patent is an old trick in the industry, used for instance by Servier and American Home Products (Wyeth) in the case of fenfluramine. Essentially, it doubles the patent life of a single drug. Admittedly, Forest Labs is bringing the active Stereoisomer on the market a year or two earlier than Celexa/Cipramil goes off patent. There are no safety or efficacy issues, only fair trade practices. See recent medical review:
Single-enantiomer drugs: elegant science, disappointing effects

Take notice that also non SSRI anti-depressants (and even Ritalin) may interact (primary or secondary) with the serotonergic (or serotoninergic) system in the brain. Every medication -especially SSRI Anti-depressants- boosting serotonin activity in the brain, has potential to induce the very dangerous and potentially fatal hyperserotonergic state of the Serotonin Syndrome.


Lexapro or Cipralex side-effects
Escitalopram  Info: Physicians
Go to Introduction Antidepressants Negative personality and perception changes, physical changes and more
Go to Antidepressant Casualties in the Media Aggression, Violent Behaviour, Homicide, Suicide and Self-Harm
Go to Recent Media Articles SSRI/SSNRI Anti-depressants Pharmaceutical Fraud & Corruption at FDA in 2004
Go to General Side-Effects SSRI/SNRI/SSNRI Antidepressants Medical Review & Reports, Cases and Studies
Lexapro/Cipralex (escitalopram) - Celexa/Cipramil (citalopram): Medical Reports, Cases & Reviews
2004 
09/14
 FDA US Antidepressant "BLACK BOX WARNING" On Suicidality Risk Recommended
2004 
05/26
 HealthCanada CELEXA WARNING: Risk of suicide, self-harm, behavioural/emotional changes
2004 
07/14
 FDA Warning FDA warning Cipralex (escitalopram): Aluminum Toxicity in interaction with linezolid
2004 
01/16
 Case/Review Severe Symptomatic Hyponatremia
2003 
12/00
 Case/Review Premature Ejaculation associated with withdrawal
2003 
08/00
 Case/Review Cardiotoxicity & Late Onset Seizures with overdose
2003 
05/00
 Case/Review Fatal Serotonin Syndrome after combined treatment with linezolid
2003 
02/00
 Case/Review Respiratory Distress Syndrome & Renal Failure with overdose
2003 
02/00
 Case/Review Antidepressant induced Cholestasis
2002 
00/00
 Case/Review Severe Hyponatraemia with Coma & Seizure
2002 
10/00
 Case/Review Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH)
2002 
09/00
 Case/Review Panic Attacks
2002 
07/00
 Case/Review Postmortem Concentrations of Citalopram
2002 
06/03
 Case/Review Perhexiline Toxicity related to Citalopram use
2002 
04/00
 Case/Review Priapism
2001 
00/00
 Case/Review Bruxism (Teeth Grinding)
2001 
12/00
 Case/Review Bradycardia, Presyncope & Hypotension
2001 
12/00
 Case/Review Photopigmentation
2001 
10/00
 Case/Review Determined to be incidental finding to ultimate Cause of Death in 11 Cases
2001 
09/00
 Case/Review Torsades de Pointes, Prolongation of QT Interval
2001 
06/07
 Case/Review Cutaneous Lesions during SSRI's therapy: 2 cases
2001 
05/06
 Case/Review QTc Interval Prolongation associated with overdose
2001 
03/00
 Case/Review A Fatal Case of Serotonin Syndrome after moclobemide-citalopram intoxication
2001 
03/00
 Case/Review BABY Withdrawal Syndrome after exposure to SSRI's
2001 
02/00
 Case/Review Severe Symptomatic Hyponatremia
2000 
10/00
 Case/Review An unusual multiple drug Fatal Intoxication case involving citalopram
2000 
10/00
 Case/Review Sexual Dysfunctions induced by SSRI's
2000 
07/00
 Case/Review Suicide Attempt Overdose: Severe Sinus Bradycardia; Pacemaker
2000 
04/00
 Case/Review Worsening of Parkinson's Disease
1999 
03/02
 Case/Review SSRI's induced Mania in obsessive compulsive disorder
1999 
02/00
 Case/Review Sinus Bradycardia
1998 
11/00
 Case/Review Autopsy cases in which Citalopram (Toxicity) alone was the Cause of Death
1997 
09/00
 Case/Review Excretion of Citalopram in Breast Milk
1997 
03/00
 Case/Review Clitoral Priapism
1996 
11/25
 Case/Review SSRI's: Hyponatremia by Schwartz-Bartter Syndrome
1996 
01/00
 Case/Review Anorgasmia
1993 
09/00
 Case/Review Significant Decrease of EEG Power of NREM sleep (8-9hz)
1983 
03/00
 Case/Review Generalized Lipidosis in Rats
1978 
00/00
 Case/Review Hepatotoxicity in Rats and first-pass metabolism
1982 
03/00
 Case/Review High dose toxicity in Dogs: Severe Convulsive Attacks, Sinus Tachycardia & Death

No Abstract, more side-effects...
2004 
01/00
 Case -No Abstract Citalopram and Dystonia
2003 
12/00
 Case -No Abstract Escitalopram-associated Mania
2002 
06/00
 Case -No Abstract Prolonged Coma after Citalopram-induced Low Sodium & Hypo-Osmolarity
2002 
01/00
 Case -No Abstract Citalopram and Psychotic Symptoms
2001 
11/12
 Case -No Abstract A clinical case of Galactorrhoea after citalopram treatment
2000 
12/00
 Case -No Abstract Serotonin Syndrome after small doses of citalopram or sertraline
2000 
10/00
 Case -No Abstract A case of citalopram Withdrawal
2000 
09/00
 Case -No Abstract Onset of Parkinson's Disease after antidepressant treatment with citalopram
2000 
03/11
 Case -No Abstract Withdrawal Syndrome and cytalopram
1998 
01/24
 Case -No Abstract Citalopram overdose may result in Serious Morbidity & Death
1994 
08/00
 Case -No Abstract Mania induced by citalopram

 Anti-Depressant Neurological Side-Effects: Addiction & Withdrawal
 Anti-Depressant Neurological Side-Effects: Akathisia & Mania (Suicide & Aggression)
 Anti-Depressant Neurological Side-Effects: Serotonin Syndrome
 Anti-Depressant Neurological Side-Effects: Toxicity & Brain Damage
 Anti-Depressant Neurological Side-Effects: "Anecdotal" Reports -Personal Experiences

 Antidepressants: How To Wean/Taper Off
 Antidepressants: How to Survive a Negative Reaction
 Antidepressants: Conquering Depression and Anxiety

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