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1: Clin Infect Dis. 2003 May 1;36(9):1197. Epub 2003 Apr 21. Related Articles, Links

Comment in: Click here to read 
Serotonin syndrome after concomitant treatment with linezolid and citalopram.

Bernard L, Stern R, Lew D, Hoffmeyer P.

Division of Orthopaedic Surgery, Geneva University Hospital, Geneva, Switzerland. louis.bernard@hcuge.ch

Linezolid, a new synthetic antimicrobial, is an important weapon against methicillin-resistant Staphylococcus aureus (MRSA). Although there are reports of serotonin syndrome developing after concomitant use of linezolid and the selective serotonin reuptake inhibitor paroxitene, this report concerns a patient receiving citalopram who developed thrombocytopenia, serotonin syndrome, and lactic acidosis and died following long-term linezolid therapy.

PMID: 12715317 [PubMed - indexed for MEDLINE]


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