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Parkinsonism & Related Disorders
Volume 6, Issue 2 , April 2000, Pages 111-113

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doi:10.1016/S1353-8020(99)00050-4    How to cite or link using doi (opens new window) Cite or link using doi  
Copyright © 2000 Elsevier Science Ltd. All rights reserved.

Worsening of Parkinson's disease by citalopram

G. LinazasoroCorresponding Author Contact Information, E-mail The Corresponding Author

Centro de Neurología y Neurocirugía funcional, Clínica Quirón, Parque Alcolea, 7 20012 San Sebastian, Guipúzcoa, Spain

Received 25 August 1999; accepted 26 August 1999. Available online 25 February 2000.


Abstract

More than 50% of the patients with Parkinson's disease (PD) may experience mood disturbances. Serotonin-selective reuptake inhibitors (SSRI) are very active in the management of depression. Citalopram is a new SSRI increasingly used in the treatment of depression. The question of a negative impact of SSRI on the motor function of patients with PD is an important clinical issue. A number of such observations have published with various SSRI, but none, up-to-now with citalopram. We report the case of a patient with PD who experienced a worsening in the motor status soon after the addition of citalopram to her antiparkinsonian drug regime. This single case report suggests that this potential adverse event is a class related side effect.

Author Keywords: Parkinson's disease; Depression; Serotonin-reuptake inhibitors; Citalopram


Corresponding Author Contact Information Fax: +34-9432-73732; email: neurotax@jet.es



This Document
Abstract
Full Text + Links
PDF (62 K)

Actions
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Parkinsonism & Related Disorders
Volume 6, Issue 2 , April 2000, Pages 111-113


 
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