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Sertraline and psychotic symptoms:
a case series.
Popli AP, Fuller MA, Jaskiw
GE.
Department of Psychiatry, Case Western Reserve
University, Cleveland, Ohio, USA.
Sertraline and other SSRIs have
a relatively favorable side-effect profile and are widely prescribed. We
report the emergence of psychotic symptoms during treatment with
sertraline in four patients. Three of these patients had a history of
psychotic illness and were on antipsychotic medication, when sertraline
was added. The psychotic symptoms emerged within 3 days-7 weeks of
starting sertraline and resolved on its discontinuation. We wish to
alert clinicians to the possibility that sertraline may provoke or
exacerbate positive psychotic symptoms, particularly in patients on
neuroleptics, with a previous history of psychosis.
Publication
Types:
PMID: 9167832 [PubMed - indexed for
MEDLINE]
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