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Sertraline-induced panic
attacks.
Catalano G, Hakala SM, Catalano
MC.
Department of Psychiatry and Behavioral Medicine,
University of South Florida College of Medicine, Tampa,
USA.
Sertraline is a selective serotonin reuptake inhibitor that
is approved by the U.S. Food and Drug Administration for the treatment
of major depression, obsessive-compulsive disorder (in adults and
children), and panic disorder. Although numerous studies have found
sertraline to be very effective in the treatment of anxiety, there have
been few case reports of panic attacks actually being induced by
treatment with sertraline. In this article, we present the cases of two
patients without any personal or family history of anxiety disorders who
developed panic attacks shortly after the initiation of sertraline
therapy. We will also review the literature in regard to the development
of anxiety symptoms during treatment with the newer antidepressants and
discuss the neurochemical basis of these antidepressant-induced panic
attacks.
Publication Types:
PMID: 10895401 [PubMed - indexed for
MEDLINE]
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