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Sertraline hepatotoxicity: a case
report and review of the literature on selective serotonin reuptake
inhibitor hepatotoxicity.
Persky S, Reinus
JF.
Division of Gastroenterology, Montefiore Medical Center,
Albert Einstein College of Medicine, Bronx, New York 10467,
USA.
The causal role of sertraline in rare cases of liver failure
in patients taking the drug has not been proven in a manner consistent
with usually accepted standards. We describe an individual who developed
clinically significant hepatitis while being treated with sertraline.
This case is significant because it is the only one of which we are
aware in which the diagnosis of sertraline hepatotoxicity was confirmed
when inadvertent rechallenge with the medication resulted in recurrent
hepatitis. We review this case and the general role of this widely
prescribed class of drugs in causing hepatitis.
Publication
Types:
- Case Reports
- Review
- Review of Reported Cases
PMID: 12772794 [PubMed -
indexed for MEDLINE]
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