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Amotivational syndrome associated
with selective serotonin reuptake inhibitors in children and
adolescents.
Garland EJ, Baerg
EA.
University of British Columbia, Mood and Anxiety
Disorders Clinic, British Columbia's Children's Hospital, Vancouver
Community Mental Health Service, Canada. jgarland@cw.bc.ca
A
frontal lobe syndrome has previously been reported in adults treated
with selective serotonin reuptake inhibitors (SSRIs), but not in
children. Five typical cases of apathy and lack of motivation, one
accompanied by disinhibition, are described in a child and four
adolescents. Symptoms were dose related and reversible. The subtlety of
symptoms, lack of insight in patients, disabling effects, and delayed
onset indicate a need for clinicians to inform families of these
potential symptoms when SSRIs are prescribed.
Publication Types:
PMID: 11436958 [PubMed - indexed for
MEDLINE]
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